Case Report Case 1 This damage is not really well understood at the moment. Lichenoid reactions. It has been shown that the most common oral manifestations are cheilitis, gingivitis, stomatitis, perioral dermatitis, burning mouth syndrome, lichenoid reaction and orofacial granulomatosis. Lichenoid Allergic Reaction. Clues that a lichenoid tissue reaction represents a lichenoid drug eruption include parakeratosis, diminished granular cell layer, and a mixed inflammatory infiltrate, including … Human oral mucosa is subjected to many noxious stimuli. These types of reactions are much less common than eczematous hypersensitivity reactions. The most important part of diagnosis is the use of patch testing that indicates contact allergic reaction … Keywords: lichenoid … Crowns and composite restorations may even suggest a lichenoid reaction in sensitive patients. Lichenoid dermatitis may occur as a result of an allergic reaction to cleaning products. Lichenoid photodermatitis is a photo-allergic reaction. Etiology: Lichenoid reactions may be caused by sensitivity to amalgam restorations, metal sensitivity such as to orthodontic wires, partials, etc. Lichenoid reactions in red organic tattoos have been shown to elicit a cytotoxic inflammatory response of the tissue [12] with lichenoid basal damage [23] thought to be produced by a delayed cellular hypersensitivity to metal particles [24]. Introduction: Utility of various dental materials ranging from diagnosis to rehabilitation for the management of oral diseases are not devoid of posing a potential risk of inducing allergic reactions to the patient, technician and dentist. There are more than 50 known pigments that … But other products may cause a hypersensitivity reaction as well in individuals. therefore the etiology of olls may represent the oral manifestation of a chronic irritation in some patients or to be the clinical result of a delayed hypersensitivity reaction in others. which in turn can cause a lichenoid pattern of reaction [22]. This damage changes how the outer layer of the skin exchange chemicals and information with the inner layer. 35-70. This paper focuses on the local toxic effects of amalgam and mercury from dental restorations. This event sets in motion the release of chemicals that can cause an allergic reaction the first time you take the drug. [4–6] Generalized lichenoid reactions to tattoos are much less common, with only four reported cases in the literature to date. Weedon, D. “The lichenoid reaction pattern (“interface dermatitis”)”. There is an established relationship between various dental materials and OLR, but few cases reports reported the occurrence of a lichenoid reaction in association with the use of a Hawley retainer. The lichenoid eruptions/photo-lichenoid eruptions clinically closely mimic lichen planus, but may have some eczematous element and usually leave a pronounced residual pigmentation. Woo, V, Bonks, J, Borukhova, L, Zegarelli, D. “Oral lichenoid drug eruption: a report of a … • This mucocutaneous disease can manifest as desquamative gingivitis, asymptomatic Wickham striae or plaques, or severe, painful erosions or ulcerations anywhere in the oral cavity. We have described two cases of lichenoid reaction developing to red ink in colored tattoos. Histologically, lichenoid drug reactions resemble lichen planus at low-power magnification. One of these substances, in those who have restorations, is dental amalgam which contains mercury. Oral lichen planus and lichenoid reaction are a common oral mucosal disease process encountered in clinical practice. Doctors give trusted, helpful answers on causes, diagnosis, symptoms, treatment, and more: Dr. Zacharisen on lichenoid allergic reaction: Not enough data. Aim: The aim of this study was to demonstrate contact allergy to dental materials in patients with oral lichenoid lesions using patch tests. Damage to the outer layer of the skin known as the epidermis. These are small ink bumps that appear on red ink marks. (An excellent text on the histopathologic findings of the lichenoid dermatitides.) Certain medications, such as those used to treat high blood pressure, hypoglycemia or arthritis, are known to cause this reaction. lichenoid lesions. Free. Oral lichenoid lesions (lichen planus-like lesions) can be induced by hypersensitivity to dental restorative metals, acrylates, flavorings and other substances. in the dermis. In their informative brief report on the treatment of oral lichenoid reaction with dental amalgam removal in a patient who received 2 mercury amalgam fillings and in whom a lichenoid contact mucositis subsequently developed, Aggarwal et al 1 found that their patient had a positive allergic reaction to 2 different amalgam allergens revealed by skin patch testing: pulverized amalgam alloy and tin. Allergies cause an increase in eosinophils in the blood to increase, and this may be partly responsible for the response of the body. An underlying medical condition or disease may also cause lichenoid dermatitis to appear. 1,2 The prevalence of LR has been reported to be approximately 2.4% in the general population and occurs in women three times more than in men. Many studies have documented contact hypersensitivity to dental materials such as amalgam (11-13), composite (14) and dental acrylics (15) presenting as lichenoid reactions. Lichenoid hypersensitivity tattoo reactions are less common than eczematous reactions. the adverse reaction from a dental restorative material can be either toxic/irritative or allergic in nature. Kamyar M. Hedayat, Jean-Claude Lapraz, in The … Some allergic reactions may result from a somewhat different process. The most common type of localized skin reaction is lichenoid, but other reaction patterns have been reported, including eczematous, granulomatous, or pseudolymphomatous. Image of a unilateral lichenoid reaction affecting the right cheek mucosa in a patient subjected to antihypertensive drug treatment. Weedon’s Skin Pathology. (2) Oral lichenoid reactions may also result from systemic drug exposure, termed as oral lichenoid drug reaction (OLDR), or local allergic contact hypersensitivity, termed as oral lichenoid contact reaction (OLCR). What Causes Lichenoid Dermatitis? Evidence exists that the lichenoid reaction is an expression of delayed hypersensitivity to a lymphocytic T-cell infiltrate, which may simulate the graft-versus-host response. This is also true with dyshidrotic dermatitis and other types of conditions caused by allergic reactions. A lichenoid eruption has been attributed to tenofovir ... [90], and an oral lichenoid reaction ... Allergic disorders. Researchers believe that some drugs can bind directly to a certain type of immune system white blood cell called a T cell. Wechsler initially reported photo-lichenoid dermatitis in the year 1954, as a photo allergic reaction to drug(s), presenting a lichenoid pattern on clinical as well as histopathological examination. Lichenoid reaction (LR) is an adverse effect which may be caused by systemic administration of drugs including antihistamine, corticosteroid and some other triggers. The signs are purple, itchy skin rashes on the skin. In relation to drug-induced lichenoid reactions, no spe-cific clinical features have been described capable of fir-mly differentiating them from lichenoid … Components of amalgam may, in rare instances, cause local side effects or allergic reactions referred to as oral lichenoid lesions (OLLs). Allergic reactions to a particular pigment can manifest in several ways including lichenoid reaction, allergic contact dermatitis and photoallergic dermatitis, granulomatous or pseudolymphoma reactions. Allergic … Oral lichenoid reaction due to nickel alloy contact hypersensitivity. Their signs and symptoms are the same as those in lichen planus, although the reaction is usually confined to the red parts of the tattoo. Mercury (red pigment) is responsible for most lichenoid tattoo reactions. 2010. pp. For reasons unknown, the two layers of skin develop an allergic reaction to each other. Treating lichenoid dermatitis successfully depends on the cause of the rash. Lichenoid reaction as an allergic reaction to dental materials has been widely reported. Lichenoid drug reaction Differential diagnosis Lichen planus: different sites (flexor arms / legs, glans penis and mucous membranes), lasts 1 - 2 years, not associated with drug administration, no prominent eosinophils ( Indian J Dermatol Venereol Leprol 2011;77:418 ) It is an expression of delayed hypersensitivity to a lymphocytic T-cell infiltrate. It is most common. The current consensus for the most common It’s the condition in which there are signs of lichenoid dermatitis (skin allergy) after exposure of the skin to sunlight. Drugs commonly linked to allergies Oral lichenoid reaction (OLR) is a type IV cell-mediated immune response in the oral cavity. So, it’s also understood as lichenoid photo-induced dermatitis. They are less common eczematous reactions. 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